Squeeze Repeats
One option that I have seldom used in tr command is -s or --squeeze-repeats:
replace each sequence of a repeated character that is listed in the last specified SET, with a single occurrence of that character - TR(1)
The best way to explain it is to demonstrate by example:
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Apply the -s option:
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The number of repeated character 1 has been squeezed into a single occurrence.
Therefore, the tr command has the following three operations:
- Translate (default, no options)
 - Delete (
-d) - Squeeze (
-s) 
To drop repeated characters, the second set is not necessary. This is very useful to remove extra spaces:
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In Vim, to squeeze the extra blank in a line:
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Additional examples from GNU Coreutils Manual.
Delete blank lines:
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Put all words on lines by themselves:
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Quick summary for above mentioned use cases:
- Remove extra spaces
 - Delete blank lines
 - Put all words on lines by themselves
 
Notes:
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